mandibular pain

Pathophysiology of Complex Orofacial Pain and Neuropathic Dental Disorders in 2026 Management of acute dental pain has historically relied on non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, and short-course opioid therapy. However, clinical dentistry in 2026 faces an evolving demographic of patients presenting with complex, refractory orofacial pain syndromes that fail standard peripheral analgesic regimens. Conditions such